MetaCyc Pathway: coenzyme M biosynthesis II in Ralstonia sp. UNC404CL21Col

Reactions and Genes	Beta-alanine (C)
	remove
O-phospho-L-serine + H⁺ + sulfite→L-cysteate + phosphate (EC 2.5.1.76)
No genes
Aspartate transaminase: L-cysteate + 2-oxoglutarate→3-sulfopyruvate + L-glutamate (EC 2.6.1.1)
ABZR87_RS04630	-0.0
ABZR87_RS05850	+0.0
ABZR87_RS05990	-0.2
ABZR87_RS08250	+0.0
ABZR87_RS08830	-0.1
ABZR87_RS08860	-0.1
ABZR87_RS09835	-0.3
ABZR87_RS11440	-0.1
ABZR87_RS14645	+0.0
ABZR87_RS17005	-0.1
ABZR87_RS18535	-0.0
ABZR87_RS19655	-4.0
ABZR87_RS21785	-0.1
Sulfopyruvate decarboxylase: 3-sulfopyruvate + H⁺→sulfoacetaldehyde + CO₂ (EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H⁺ + H₂O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H⁺→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H₂O→coenzyme M + ammonium + pyruvate
No genes

Links:

Pathway details at MetaCyc
Fitness data for 13 genes
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All MetaCyc pathways for Ralstonia sp. UNC404CL21Col

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information