MetaCyc Pathway: L-lysine degradation IV in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes L-Arginine (C)
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Lysine 2-monooxygenase:
L-lysine + dioxygen→5-aminopentanamide + CO2 + H2O (EC 1.13.12.2)
AO353_07420 -0.0
5-aminopentanamidase:
5-aminopentanamide + H2O→5-aminopentanoate + ammonium (EC 3.5.1.30)
AO353_07425 -0.0
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
AO353_11510 -0.4
AO353_28215 +0.1
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
AO353_11505 -1.3
AO353_28230 -0.2
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate (EC 2.8.3.13)
AO353_11105 -0.1
AO353_23060 +0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information