MetaCyc Pathway: L-arginine biosynthesis II (acetyl cycle) in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes L-Arginine (C)
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Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
AO353_02900 -0.0
AO353_08590 +0.2
AO353_08595 -2.8
AO353_12170 N.D.
AO353_24780 -0.0
AO353_24910 -0.1
AO353_27475 -0.1
AO353_27900 +0.1
AO353_29300 -0.2
Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
AO353_03670 -0.8
AO353_08685 -0.7
AO353_10000 -0.1
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
AO353_09240 -0.0
Carbamoyl-phosphate synthase (glutamine-hydrolyzing):
L-glutamine + 2 ATP + hydrogen carbonate + H2O→L-glutamate + carbamoyl phosphate + 2 ADP + 2 H+ + phosphate (EC 6.3.5.5)
AO353_05630 N.D.
AO353_05635 N.D.
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
AO353_07155 -0.8
Ornithine carbamoyltransferase:
carbamoyl phosphate + L-ornithine→L-citrulline + H+ + phosphate (EC 2.1.3.3)
AO353_03475 +0.1
AO353_04155 -0.1
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
AO353_03025 -3.8
AO353_07470 +0.1
AO353_10500 +0.1
AO353_15640 -0.2
AO353_28215 +0.1
Argininosuccinate synthase:
L-citrulline + ATP + L-aspartate→L-arginino-succinate + AMP + diphosphate + H+ (EC 6.3.4.5)
AO353_04105 -0.2
Argininosuccinate lyase:
L-arginino-succinate→L-arginine + fumarate (EC 4.3.2.1)
AO353_09000 -1.5
AO353_25585 +0.4
Glutamate N-acetyltransferase:
L-glutamate + N-acetyl-L-ornithine→N-acetyl-L-glutamate + L-ornithine (EC 2.3.1.35)
AO353_03670 -0.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information