MetaCyc Pathway: L-tyrosine degradation III in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes L-Phenylalanine (C)
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Pf6N2E2_1496 +0.0
Pf6N2E2_2127 -0.1
Pf6N2E2_2446 -0.0
Pf6N2E2_2519 -0.2
Pf6N2E2_2632 -3.3
Pf6N2E2_3173 +0.1
Pf6N2E2_3251 -3.5
Pf6N2E2_4288 -0.2
Pf6N2E2_4386 +0.0
Pf6N2E2_462 +0.0
Pf6N2E2_50 +0.2
Pf6N2E2_5300 -0.2
Pf6N2E2_5813 +0.1
Pf6N2E2_5890 -0.1
Pf6N2E2_5891 N.D.
Pf6N2E2_5895 -0.1
Pf6N2E2_5989 -0.4
Pf6N2E2_637 +0.2
Pf6N2E2_684 +0.1
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1)
Pf6N2E2_1380 N.D.
Pf6N2E2_1522 -0.1
Pf6N2E2_194 -0.0
Pf6N2E2_2802 +0.0
Pf6N2E2_3044 -0.2
Pf6N2E2_4819 -0.1
Pf6N2E2_5980 +0.1
Pf6N2E2_840 -0.2
Pf6N2E2_999 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information