MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Azospirillum brasilense Sp245

Add experiment(s):


Reactions and Genes L-Leucine (N)
remove
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
AZOBR_RS06555 -2.3
AZOBR_RS07050 -0.1
AZOBR_RS07650 -0.3
AZOBR_RS07830 N.D.
AZOBR_RS08675 +0.2
AZOBR_RS12970 N.D.
AZOBR_RS16760 -0.2
AZOBR_RS20195 +0.1
AZOBR_RS22530 -0.2
AZOBR_RS24065 +0.0
AZOBR_RS27565 +0.2
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information