MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Azospirillum brasilense Sp245

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Reactions and Genes L-Leucine (N)
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Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
AZOBR_RS30515 +1.0
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
AZOBR_RS06845 +0.1
AZOBR_RS21415 +0.0
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
AZOBR_RS30515 +1.0
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
AZOBR_RS14060 N.D.
AZOBR_RS16020 -0.2
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
AZOBR_RS08350 N.D.
AZOBR_RS08650 -1.5
AZOBR_RS23385 -0.0
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
AZOBR_RS06555 -2.3
AZOBR_RS07050 -0.1
AZOBR_RS07650 -0.3
AZOBR_RS07830 N.D.
AZOBR_RS12970 N.D.
AZOBR_RS16760 -0.2
AZOBR_RS20195 +0.1
AZOBR_RS22530 -0.2
AZOBR_RS24065 +0.0
AZOBR_RS27565 +0.2
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
AZOBR_RS06120 -0.2
AZOBR_RS10315 -0.9
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
AZOBR_RS14390 N.D.
AZOBR_RS22245 N.D.
AZOBR_RS22250 N.D.
AZOBR_RS25395 -0.4
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
AZOBR_RS24070 +0.1
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
AZOBR_RS21115 -0.2
AZOBR_RS24250 -0.0
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
AZOBR_RS14065 +0.4
AZOBR_RS14070 +0.1
AZOBR_RS32480 -0.3
AZOBR_RS32485 -0.3
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
AZOBR_RS07250 -0.6
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
AZOBR_RS03260 N.D.
AZOBR_RS21100 -0.8
AZOBR_RS21105 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information