MetaCyc Pathway: glutathione-mediated detoxification II in Shewanella sp. ANA-3

Reactions and Genes	casaminos (C)
Glutathione transferase: RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
Shewana3_0013	-0.1
Shewana3_0755	+0.1
Shewana3_2777	-3.3
Shewana3_2865	+0.2
Shewana3_2866	-0.1
Shewana3_3519	-0.1
Shewana3_4049	-0.3
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→a [γ-glutamyl-L-cysteine]-S-conjugate + glycine (EC 3.4.17.25)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
a [γ-glutamyl-L-cysteine]-S-conjugate + H2O→an L-cysteine-S-conjugate + L-glutamate (EC 3.4.13.M2)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
an L-cysteine-S-conjugate + malonyl-CoA→an N-malonyl-L-cysteine-S-conjugate + coenzyme A + H+
No genes
Cysteine-S-conjugate beta-lyase: an L-cysteine-S-conjugate + H2O→a thiol + ammonium + pyruvate (EC 4.4.1.13)
No genes
Thiol S-methyltransferase: a thiol + S-adenosyl-L-methionine→a methyl thioether + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.9)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information