MetaCyc Pathway: superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) in Pseudomonas fluorescens FW300-N2E3

Add experiment(s):


Reactions and Genes Cisplatin 0.006 mg/ml
remove
NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29)
AO353_23605 N.D.
Aldehyde dehydrogenase (NADP(+)):
NADP+ + an aldehyde + H2O→NADPH + a carboxylate + 2 H+ (EC 1.2.1.4)
AO353_22335 +0.0
Aldehyde dehydrogenase (NAD(+)):
NAD+ + an aldehyde + H2O→NADH + a carboxylate + 2 H+ (EC 1.2.1.3)
AO353_03860 +0.5
AO353_05300 +0.3
AO353_06560 -0.2
AO353_08290 -0.1
AO353_09195 +2.9
AO353_13330 -0.3
AO353_15035 +0.4
AO353_19510 +0.3
AO353_22335 +0.0
AO353_22390 -0.6
AO353_23135 -0.1
AO353_24855 -0.2
AO353_24905 -0.1
AO353_28290 +0.2
Glucose-6-phosphate dehydrogenase:
NADP+ + D-glucopyranose 6-phosphate→NADPH + 6-phospho D-glucono-1,5-lactone + H+ (EC 1.1.1.49)
AO353_03360 -0.6
AO353_25830 -0.1
Isocitrate dehydrogenase (NADP(+)):
NADP+ + D-threo-isocitrate→NADPH + 2-oxoglutarate + CO2 (EC 1.1.1.42)
AO353_27690 -0.6
AO353_27695 -1.5
Aldehyde dehydrogenase (NADP(+)):
NADP+ + acetaldehyde + H2O→NADPH + acetate + 2 H+ (EC 1.2.1.4)
No genes
NADH kinase:
NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29)
No genes
NADH[in] + H+[in] + a ubiquinone→NAD+[in] + a ubiquinol (EC 1.6.5.9)
AO353_14255 +0.0
AO353_23580 +0.5

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information