MetaCyc Pathway: aerobactin biosynthesis in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes Cisplatin 0.006 mg/ml
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L-lysine 6-monooxygenase (NADPH):
L-lysine + NADPH + dioxygen→N6-hydroxy-L-lysine + NADP+ + H2O (EC 1.14.13.59)
AO353_24010 -1.0
N(6)-hydroxylysine O-acetyltransferase:
N6-hydroxy-L-lysine + acetyl-CoA→N6-acetyl-N6-hydroxy-L-lysine + coenzyme A (EC 2.3.1.102)
No genes
N6-acetyl-N6-hydroxy-L-lysine + ATP + citrate→N1-citryl-N6-acetyl-N6-hydroxy-L-lysine + AMP + diphosphate + H+ (EC 6.3.2.38)
No genes
N1-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + ATP→aerobactin + AMP + diphosphate + H+ (EC 6.3.2.39)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information