MetaCyc Pathway: dTDP-4-O-demethyl-β-L-noviose biosynthesis in Dyella japonica UNC79MFTsu3.2

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Reactions and Genes D-Galactose (C)
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Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)
ABZR86_RS09505 +0.0
ABZR86_RS18730 +2.0
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46)
ABZR86_RS09700 +0.0
ABZR86_RS10000 +0.7
ABZR86_RS16185 -0.2
ABZR86_RS18505 +0.3
ABZR86_RS18735 +2.2
dTDP-4-dehydrorhamnose 3,5-epimerase:
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose→dTDP-4-dehydro-β-L-rhamnose (EC 5.1.3.13)
ABZR86_RS10015 +0.9
ABZR86_RS18725 +0.1
dTDP-4-dehydro-β-L-rhamnose + S-adenosyl-L-methionine→dTDP-4-dehydro-5-methyl-β-L-rhamnose + S-adenosyl-L-homocysteine + H+
ABZR86_RS10010 +1.3
dTDP-4-dehydro-5-methyl-β-L-rhamnose + NADH + H+→dTDP-4-O-demethyl-β-L-noviose + NAD+
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information