MetaCyc Pathway: L-tyrosine biosynthesis I in Bifidobacterium breve UCC2003

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Reactions and Genes CDM1 without Alanine
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Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
BBR_RS11770 -2.2
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH
(EC 1.3.1.12)
BBR_RS16675 -3.3
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
BBR_RS13205 -0.2
BBR_RS13460 -0.2
BBR_RS14535 -0.1
BBR_RS15505 -0.9
BBR_RS15560 -3.7
BBR_RS17050 +0.2
BBR_RS17345 -0.2
BBR_RS17965 -0.1
BBR_RS19435 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information