| Reactions and Genes | Cisplatin 0.006 mg/ml |
|---|
| remove |
| a phytoceramide + 2 a ferrocytochrome b5 + dioxygen + 2 H+→a (2'R)-2'-hydroxy-phytoceramide + 2 a ferricytochrome b5 + H2O (EC 1.14.18.6) |
| No genes |
Ceramidase:
a (2'R)-2'-hydroxy-phytoceramide + H2O→a (2R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + a phytosphingosine (EC 3.5.1.23) |
| No genes |
| a (2R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A→a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
| a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA→formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde (EC 4.1.2.63) |
| No genes |
Formyl-CoA hydrolase:
formyl-CoA + H2O→formate + coenzyme A + H+ (EC 3.1.2.10) |
| No genes |
Aldehyde dehydrogenase (NAD(+)):
an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O→an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ (EC 1.2.1.3) |
| AO353_03860 | +0.1 |
| AO353_05300 | +0.4 |
| AO353_06560 | +0.1 |
| AO353_08290 | -0.0 |
| AO353_09195 | +2.7 |
| AO353_13330 | -0.2 |
| AO353_15035 | +0.5 |
| AO353_19510 | -0.2 |
| AO353_22390 | -0.3 |
| AO353_23135 | +0.2 |
| AO353_24855 | -0.3 |
| AO353_24905 | -0.1 |
| AO353_28290 | +0.5 |
Long-chain-fatty-acid--CoA ligase:
an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A→an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate (EC 6.2.1.3) |
| AO353_02215 | +0.2 |
| AO353_03310 | +0.2 |
| AO353_03315 | -0.0 |
| AO353_20355 | +0.0 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information