MetaCyc Pathway: myo-inositol degradation I in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes D-Fructose (C)
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Inositol 2-dehydrogenase:
myo-inositol + NAD+→scyllo-inosose + NADH + H+ (EC 1.1.1.18)
Pf6N2E2_1002 +8.2
Pf6N2E2_1791 -0.4
Pf6N2E2_518 +0.5
Pf6N2E2_519 -0.2
Pf6N2E2_543 +0.2
Pf6N2E2_885 -0.0
Myo-inosose-2 dehydratase:
scyllo-inosose→3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O (EC 4.2.1.44)
Pf6N2E2_513 +0.5
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O→5-deoxy-D-glucuronate + H+ (EC 3.7.1.22)
Pf6N2E2_517 +0.6
5-deoxy-D-glucuronate→5-dehydro-2-deoxy-D-gluconate (EC 5.3.1.30)
Pf6N2E2_514 +0.9
5-dehydro-2-deoxygluconokinase:
5-dehydro-2-deoxy-D-gluconate + ATP→5-dehydro-2-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.92)
Pf6N2E2_512 +0.1
Pf6N2E2_514 +0.9
5-dehydro-2-deoxyphosphogluconate aldolase:
5-dehydro-2-deoxy-D-gluconate 6-phosphate→glycerone phosphate + 3-oxopropanoate (EC 4.1.2.29)
Pf6N2E2_512 +0.1
Malonate-semialdehyde dehydrogenase (acetylating):
3-oxopropanoate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH (EC 1.2.1.18)
Pf6N2E2_3452 -0.3
Pf6N2E2_3462 -0.2
Pf6N2E2_515 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information