MetaCyc Pathway: adipate degradation in Pseudomonas stutzeri RCH2

Reactions and Genes	butyrate (C)
Succinate--CoA ligase (ADP-forming): adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate (EC 6.2.1.5)
Psest_2490	+0.3
Psest_2491	+0.1
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
Psest_3968	-0.9
Psest_0417	+2.7
Psest_0419	-3.6
Psest_0539	+0.8
Enoyl-CoA hydratase (in reverse): (2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17)
Psest_2076	+0.1
Psest_2437	-0.1
Psest_2439	-0.6
Psest_2654	N.D.
Psest_2720	+0.8
Psest_3109	+0.2
Psest_3110	+0.3
Psest_3800	+0.2
Psest_3969	+0.1
Psest_4235	+0.5
3-hydroxyacyl-CoA dehydrogenase: (3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+ (EC 1.1.1.35)
Psest_2654	N.D.
Psest_3109	+0.2
Psest_3800	+0.2
Psest_3969	+0.1
Psest_4235	+0.5
3-oxoadipyl-CoA thiolase (in reverse): 3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174)
Psest_3070	+0.3

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information