MetaCyc Pathway: γ-glutamyl cycle in Shewanella amazonensis SB2B

Reactions and Genes	L-Glutamine
5-oxoprolinase (ATP-hydrolyzing): 5-oxo-L-proline + ATP + 2 H2O→L-glutamate + ADP + H+ + phosphate (EC 3.5.2.9)
Sama_0021	-0.5
Sama_0022	-0.2
Glutamate--cysteine ligase: L-glutamate + L-cysteine + ATP→γ-L-glutamyl-L-cysteine + ADP + H+ + phosphate (EC 6.3.2.2)
Sama_1058	-1.2
Glutathione synthase: γ-L-glutamyl-L-cysteine + ATP + glycine→glutathione + ADP + H+ + phosphate (EC 6.3.2.3)
Sama_0574	-1.8
Gamma-glutamyltransferase: glutathione + a proteinogenic amino acid→an α-(γ-L-glutamyl)-L-amino acid + L-cysteinylglycine (EC 2.3.2.2)
Sama_0669	+0.0
Sama_1566	-1.4
an α-(γ-L-glutamyl)-L-amino acid→5-oxo-L-proline + an L-amino acid (EC 4.3.2.9)
No genes
Cytosol nonspecific dipeptidase: L-cysteinylglycine + H2O→L-cysteine + glycine (EC 3.4.13.18)
Sama_0795	-1.5
Sama_1586 (pepN)	+0.1
Sama_2519	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information