MetaCyc Pathway: gallate degradation III (anaerobic) in Phaeobacter inhibens DSM 17395

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Reactions and Genes m.b. Vancomycin 0.032 mg/ml
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Gallate decarboxylase:
gallate + H+→pyrogallol + CO2 (EC 4.1.1.59)
No genes
Pyrogallol hydroxytransferase:
pyrogallol + 1,2,3,5-tetrahydroxybenzene→phloroglucinol + 1,2,3,5-tetrahydroxybenzene (EC 1.97.1.2)
No genes
Phloroglucinol reductase (in reverse):
phloroglucinol + NADPH + H+→dihydrophloroglucinol + NADP+ (EC 1.3.1.57)
No genes
dihydrophloroglucinol + H2O→3-hydroxy-5-oxohexanoate + H+
No genes
Acetate CoA-transferase (in reverse):
3-hydroxy-5-oxohexanoate + acetyl-CoA→acetate + 3-hydroxy-5-oxohexanoyl-CoA (EC 2.8.3.8)
No genes
3-hydroxy-5-oxohexanoyl-CoA + coenzyme A→acetyl-CoA + (S)-3-hydroxybutanoyl-CoA
No genes
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
PGA1_c14440 +0.2
PGA1_c15660 +0.7
PGA1_c16990 -0.4
PGA1_c22740 +0.1
PGA1_c23460 -0.1
PGA1_c26820 -1.3
PGA1_c36500 N.D.
PGA1_262p01540 -0.4
PGA1_262p01850 +0.1
PGA1_262p01980 +0.0
PGA1_c04110 -1.7
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
acetate + butanoyl-CoA→acetyl-CoA + butanoate (EC 2.8.3.1; 2.8.3.8)
No genes
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
PGA1_c28850 +0.2
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
PGA1_c28840 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information