MetaCyc Pathway: chorismate biosynthesis from 3-dehydroquinate in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes Quinic Acid (C)
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3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
PFLU_RS03050 N.D.
PFLU_RS06375 N.D.
PFLU_RS09395 -0.0
PFLU_RS20995 -0.1
PFLU_RS26355 -1.9
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
PFLU_RS00120 N.D.
PFLU_RS10495 +0.1
PFLU_RS26360 -1.4
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
PFLU_RS02025 N.D.
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
PFLU_RS08105 +0.1
PFLU_RS13540 -1.2
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
PFLU_RS21280 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information