MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes D-(+)-Galactosamine (C)
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glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)
PFLU_RS02080 -0.2
PFLU_RS03220 -0.1
PFLU_RS05335 +0.0
PFLU_RS05340 +0.0
PFLU_RS09615 +0.2
PFLU_RS09635 -0.4
PFLU_RS09805 -0.1
PFLU_RS09810 +0.1
PFLU_RS12555 +0.1
PFLU_RS14865 +0.1
PFLU_RS14960 -0.6
PFLU_RS15050 +0.2
PFLU_RS15565 +0.4
PFLU_RS15990 -0.7
PFLU_RS16275 +0.2
PFLU_RS17200 -0.0
PFLU_RS18190 +0.2
PFLU_RS19495 -0.1
PFLU_RS22760 -0.1
PFLU_RS22960 -2.8
PFLU_RS23055 N.D.
PFLU_RS30525 -0.5
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)
PFLU_RS06330 N.D.
PFLU_RS09035 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)
PFLU_RS14490 -0.0
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
PFLU_RS27645 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information