MetaCyc Pathway: 4-hydroxy-2-nonenal detoxification in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Ying_AminoAcid20 rep A; time point 2
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Glutathione transferase:
4-hydroxy-2-nonenal + glutathione→(glutathion-S-yl)-4-hydroxy-2-nonenal (EC 2.5.1.18)
Pf6N2E2_1445 -0.2
Pf6N2E2_1553 -0.7
Pf6N2E2_1561 +0.2
Pf6N2E2_1619 -0.2
Pf6N2E2_2148 +0.3
Pf6N2E2_2168 -1.5
Pf6N2E2_303 +0.0
Pf6N2E2_395 -0.2
Pf6N2E2_4178 -0.3
Pf6N2E2_4235 +0.1
Pf6N2E2_4428 +0.3
Pf6N2E2_509 -0.5
Pf6N2E2_5292 -1.4
Pf6N2E2_5412 +0.1
Pf6N2E2_5517 -1.2
Pf6N2E2_5974 -0.2
Pf6N2E2_6007 +0.1
Pf6N2E2_933 +0.0
(glutathion-S-yl)-4-hydroxy-2-nonenal + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + L-glutamate (EC 3.4.19.13)
No genes
S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteine + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
S-(4-hydroxy-nonenal-3-yl)-L-cysteine + acetyl-CoA→4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ (EC 2.3.1.80)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information