MetaCyc Pathway: caffeine degradation IV (bacteria, via demethylation and oxidation) in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Ying_Nucleobase14 rep C; time point 1
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caffeine + NAD(P)H + dioxygen + H+→theobromine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.178)
No genes
theobromine + dioxygen + H2O→3,7-dimethylurate + hydrogen peroxide
No genes
caffeine + NAD(P)H + dioxygen + H+→paraxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.179)
No genes
theobromine + NAD(P)H + dioxygen + H+→7-methylxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.179)
No genes
paraxanthine + NAD(P)H + dioxygen + H+→7-methylxanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.178)
No genes
paraxanthine + dioxygen + H2O→1,7-dimethylurate + hydrogen peroxide
No genes
7-methylxanthine + NAD(P)H + dioxygen + H+→xanthine + formaldehyde + NAD(P)+ + H2O (EC 1.14.13.128)
No genes
7-methylxanthine + dioxygen + H2O→7-methylurate + hydrogen peroxide
No genes
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
Pf6N2E2_2336 -0.5
Pf6N2E2_2337 -1.1
Xanthine oxidase:
xanthine + dioxygen + H2O→urate + hydrogen peroxide (EC 1.17.3.2)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information