MetaCyc Pathway: L-phenylalanine degradation VI (reductive Stickland reaction) in Pseudomonas fluorescens SBW25-INTG

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Reactions and Genes L-tyrosine (C) 10 mM
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Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
PFLU_RS04475 -1.1
PFLU_RS08100 +0.3
PFLU_RS08510 -0.1
PFLU_RS09125 +0.1
PFLU_RS10980 +0.1
PFLU_RS13455 +0.0
PFLU_RS15480 -0.1
PFLU_RS16880 -0.0
PFLU_RS17055 +0.1
PFLU_RS17810 -0.3
PFLU_RS19680 -0.1
PFLU_RS20660 +0.2
PFLU_RS21080 -0.1
PFLU_RS21355 +0.1
PFLU_RS21880 -2.9
PFLU_RS22640 -0.0
PFLU_RS22895 +1.8
PFLU_RS24775 +0.0
PFLU_RS25195 -0.0
PFLU_RS29405 -0.2
PFLU_RS29850 -0.1
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(phenyl)lactate + (E)-cinnamoyl-CoA→(R)-3-(phenyl)lactoyl-CoA + trans-cinnamate (EC 2.8.3.17)
No genes
trans-cinnamate + a reduced electron-transfer flavoprotein→3-phenylpropanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(phenyl)lactoyl-CoA→(E)-cinnamoyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information