MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Pseudomonas fluorescens SBW25-INTG

Add experiment(s):


Reactions and Genes L-Valine 10 mM (C)
remove
Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
PFLU_RS07105 +0.5
PFLU_RS07650 -2.3
PFLU_RS08485 -0.2
PFLU_RS10835 -1.4
PFLU_RS12025 -0.4
PFLU_RS13550 +0.1
PFLU_RS14775 -5.1
PFLU_RS14785 -3.2
PFLU_RS16080 +0.1
PFLU_RS22820 +0.0
PFLU_RS22840 +0.2
PFLU_RS24260 -0.5
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
PFLU_RS16075 +1.2
PFLU_RS16110 +0.0
PFLU_RS20100 +0.2

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information