MetaCyc Pathway: 2-nitrobenzoate degradation I in Burkholderia phytofirmans PsJN

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Reactions and Genes Parafilmed volatile agar plate with Trichoderma atroviridae IMI ago3mutant
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2-nitrobenzoate + 2 NADPH + 2 H+→2-hydroxylaminobenzoate + 2 NADP+ + H2O
BPHYT_RS26105 +2.0
2-hydroxylaminobenzoate→3-hydroxyanthranilate
BPHYT_RS13355 N.D.
3-hydroxyanthranilate 3,4-dioxygenase:
3-hydroxyanthranilate + dioxygen→2-amino-3-carboxymuconate-6-semialdehyde (EC 1.13.11.6)
BPHYT_RS07265 +0.6
Aminocarboxymuconate-semialdehyde decarboxylase:
2-amino-3-carboxymuconate-6-semialdehyde + H+→(2Z,4E)-2-amino-6-oxohexa-2,4-dienoate + CO2 (EC 4.1.1.45)
BPHYT_RS07270 N.D.
Aminomuconate-semialdehyde dehydrogenase:
(2Z,4E)-2-amino-6-oxohexa-2,4-dienoate + NAD+ + H2O→(2Z,4E)-2-aminomuconate + NADH + 2 H+ (EC 1.2.1.32)
BPHYT_RS07235 -0.5
2-aminomuconate deaminase:
(2Z,4E)-2-aminomuconate + H2O→(3E)-2-oxohex-3-enedioate + ammonium (EC 3.5.99.5)
BPHYT_RS07260 N.D.
4-oxalocrotonate decarboxylase:
(3E)-2-oxohex-3-enedioate + H+→(2Z)-2-hydroxypenta-2,4-dienoate + CO2 (EC 4.1.1.77)
BPHYT_RS07240 N.D.
BPHYT_RS07255 +0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information