| Reactions and Genes | Sebacic (C); anaerobic |
|---|
| remove |
| arachidonoyl-CoA + malonyl-CoA + H+→(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+→(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA→(2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + NADPH + H+→adrenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
| adrenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA→(2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| No genes |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA (EC 4.2.1.17) |
| TX73_001990 | -0.1 |
| TX73_002165 | -0.0 |
| TX73_002395 | +0.1 |
| TX73_002500 | +0.1 |
| TX73_002510 | +0.0 |
| TX73_003370 | +0.0 |
| TX73_003500 | -0.0 |
| TX73_004220 | -0.0 |
| TX73_004930 | +0.2 |
| TX73_006355 | +0.1 |
| TX73_007240 | +0.4 |
| TX73_008780 | +0.2 |
| TX73_008810 | -0.0 |
| TX73_009040 | -0.1 |
| TX73_009055 | +0.3 |
| TX73_009075 | +0.1 |
| TX73_009185 | +0.1 |
| TX73_009315 | -0.2 |
| TX73_011065 | +0.2 |
| TX73_011975 | +0.0 |
| TX73_014325 | +0.2 |
| TX73_017085 | -0.0 |
| TX73_017810 | -0.3 |
| TX73_017840 | -0.3 |
| TX73_017875 | +0.2 |
| TX73_019255 | -1.4 |
| TX73_019650 | -0.1 |
| TX73_022390 | -0.1 |
| TX73_022490 | +0.3 |
| (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| TX73_002660 | +0.1 |
| TX73_002750 | -0.1 |
| TX73_004215 | -0.1 |
| TX73_008765 | +0.2 |
| TX73_011915 | +0.2 |
| TX73_017920 | +0.1 |
| TX73_017940 | -0.1 |
| TX73_019245 | -1.2 |
| TX73_022530 | +0.0 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information