MetaCyc Pathway: 2-oxobutanoate degradation I in Rhodopseudomonas palustris CGA009

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Reactions and Genes Citraconic (C); anaerobic
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2-oxoisovalerate dehydrogenase (acylating):
2-oxobutanoate + coenzyme A + NAD+→propanoyl-CoA + CO2 + NADH (EC 1.2.1.25)
No genes
Propionyl-CoA carboxylase:
propanoyl-CoA + ATP + hydrogen carbonate→(S)-methylmalonyl-CoA + ADP + H+ + phosphate (EC 6.4.1.3)
TX73_000370 N.D.
TX73_002635 N.D.
TX73_016420 -4.3
TX73_016565 -5.3
TX73_017885 -0.0
Methylmalonyl-CoA epimerase (in reverse):
(S)-methylmalonyl-CoA→(R)-methylmalonyl-CoA (EC 5.1.99.1)
TX73_015205 -2.1
Methylmalonyl-CoA mutase:
(R)-methylmalonyl-CoA→succinyl-CoA (EC 5.4.99.2)
TX73_009435 -4.6
TX73_009445 -4.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information