MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Rhodopseudomonas palustris CGA009

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Reactions and Genes Citraconic (C); anaerobic
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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
TX73_001990 +0.0
TX73_002165 -0.1
TX73_002395 -0.0
TX73_002500 -0.0
TX73_002510 +0.1
TX73_003370 +0.0
TX73_003500 +0.2
TX73_004220 -0.1
TX73_004930 +0.0
TX73_006355 +0.1
TX73_007240 +0.1
TX73_008780 +0.1
TX73_008810 +0.2
TX73_009040 -0.0
TX73_009055 -0.1
TX73_009075 -0.1
TX73_009185 -0.1
TX73_009315 +0.3
TX73_011065 +0.1
TX73_011975 +0.0
TX73_014325 +0.2
TX73_017085 +0.1
TX73_017810 -0.0
TX73_017840 +0.3
TX73_017875 +0.1
TX73_019255 +0.1
TX73_019650 -0.0
TX73_022390 -0.1
TX73_022490 +0.2
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
TX73_004220 -0.1
TX73_008775 -0.0
TX73_011910 -0.3
TX73_018155 -0.2
TX73_019255 +0.1
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
TX73_002660 +0.3
TX73_002750 -0.1
TX73_004215 +0.1
TX73_008765 -0.0
TX73_011915 +0.1
TX73_017920 +0.1
TX73_017940 +0.1
TX73_019245 -0.1
TX73_022530 +0.0
benzoyl-CoA + H2O→benzoate + coenzyme A + H+
No genes
benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)
No genes
benzyl benzoate + H2O→benzoate + benzyl alcohol + H+
No genes
Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)
TX73_003425 -1.1
TX73_003465 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information