MetaCyc Pathway: NAD(P)/NADPH interconversion in Mycobacterium tuberculosis H37Rv

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Reactions and Genes L-Asparagine (C)
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29)
Rv1695 N.D.
NADP+ + H2O→NAD+ + phosphate (EC 3.1.3.108)
No genes
NAD+[in] + 4 H+[out] + a ubiquinol→NADH[in] + 5 H+[in] + a ubiquinone (EC 7.1.1.2)
Rv0392c -0.0
Rv1812c +0.2
Rv1854c N.D.
Rv3145 -1.7
Rv3146 -1.4
Rv3148 -1.1
Rv3149 -1.4
Rv3150 -1.4
Rv3151 -1.5
Rv3152 -1.2
Rv3153 -1.3
Rv3154 -1.3
Rv3155 N.D.
Rv3156 -1.4
Rv3157 -1.6
Rv3158 -1.5
NAD(P)(+) transhydrogenase (B-specific):
NAD+ + NADPH→NADH + NADP+ (EC 1.6.1.1; 1.6.1.3)
Rv0155 -0.3
Rv0156 N.D.
Rv0157 -0.6
Rv2713 +0.0
NADPH + H2O→NADH + phosphate (EC 3.1.3.108)
No genes
NADH kinase:
NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information