MetaCyc Pathway: superpathway of Clostridium acetobutylicum acidogenic fermentation in Mycobacterium tuberculosis H37Rv

Reactions and Genes	Glycerol (C)
Pyruvate synthase: pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase: 2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
Rv0243	-1.6
Rv0859	N.D.
Rv0914c	-0.2
Rv1074c	+0.2
Rv1135A	N.D.
Rv1323	-0.4
Rv1867	+0.2
Rv2790c	-0.1
Rv3523	+0.1
Rv3546	-0.2
Rv3556c	+0.7
Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
Rv0408	+0.1
Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
Rv0409	+0.1
3-hydroxyacyl-CoA dehydrogenase (in reverse): acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
Rv0468	-0.1
Rv0860	N.D.
Rv1144	-0.1
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
Rv0222	-0.1
Rv0456c	-0.2
Rv0632c	-0.2
Rv0675	-1.7
Rv0905	-0.3
Rv1070c	-0.4
Rv1136	N.D.
Rv1141c	+0.1
Rv1142c	-0.2
Rv1472	-0.1
Rv1935c	+0.1
Rv2486	-0.1
Rv2679	-0.3
Rv2831	-0.3
Rv3039c	-0.2
Rv3373	N.D.
Rv3374	+0.1
Rv3516	+0.1
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
Rv3029c	N.D.
Phosphate butyryltransferase: butanoyl-CoA + phosphate→butanoyl phosphate + coenzyme A (EC 2.3.1.19)
No genes
Branched-chain-fatty-acid kinase (in reverse): butanoyl phosphate + ADP→butanoate + ATP (EC 2.7.2.14; 2.7.2.7)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information