MetaCyc Pathway: superpathway of L-arginine and L-ornithine degradation in Pseudomonas fluorescens FW300-N2E3

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Reactions and Genes Paraquat dichloride 0.032 mg/mL
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Arginine decarboxylase:
L-arginine + H+→agmatine + CO2 (EC 4.1.1.19)
AO353_05445 -0.0
AO353_13720 -0.3
AO353_23560 +0.5
Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)
AO353_05445 -0.0
Agmatinase:
agmatine + H2O→putrescine + urea (EC 3.5.3.11)
AO353_18400 -0.1
Putrescine aminotransferase:
putrescine + 2-oxoglutarate→4-aminobutanal + L-glutamate (EC 2.6.1.82)
AO353_17760 -0.2
Glutamate--putrescine ligase:
putrescine + ATP + L-glutamate→γ-glutamyl-L-putrescine + ADP + H+ + phosphate (EC 6.3.1.11)
AO353_08595 -0.4
AO353_29300 -0.2
Aminobutyraldehyde dehydrogenase:
4-aminobutanal + NAD+ + H2O→4-aminobutanoate + NADH + 2 H+ (EC 1.2.1.19)
AO353_03860 +0.4
AO353_04265 +0.0
AO353_04290 +0.3
AO353_06560 +0.1
AO353_09195 +8.2
AO353_15035 -0.1
AO353_19510 -0.1
AO353_22390 +0.2
AO353_23135 -0.3
AO353_24855 +0.5
AO353_24905 -0.1
AO353_28290 +0.2
AO353_29295 -0.1
4-aminobutanal→1-pyrroline + H2O (spontaneous)
No genes
γ-glutamyl-L-putrescine + dioxygen + H2O→4-(γ-L-glutamylamino)butanal + ammonium + hydrogen peroxide (EC 1.4.3.M3)
AO353_20720 +0.1
AO353_29290 +0.0
4-(γ-L-glutamylamino)butanal + NAD(P)+ + H2O→4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ (EC 1.2.1.99)
No genes
Gamma-glutamyl-gamma-aminobutyrate hydrolase:
4-(γ-L-glutamylamino)butanoate + H2O→4-aminobutanoate + L-glutamate (EC 3.5.1.94)
AO353_29305 +0.2
4-aminobutyrate transaminase:
4-aminobutanoate + 2-oxoglutarate→succinate semialdehyde + L-glutamate (EC 2.6.1.19)
AO353_08585 +0.1
AO353_10500 -0.3
AO353_11510 +0.4
AO353_11905 +0.0
AO353_28215 +0.2
Succinate-semialdehyde dehydrogenase:
succinate semialdehyde + NAD+ + H2O→succinate + NADH + 2 H+ (EC 1.2.1.24)
No genes
succinate semialdehyde + NADP+ + H2O→succinate + NADPH + 2 H+ (EC 1.2.1.79)
AO353_28230 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information