MetaCyc Pathway: superpathway of sulfate assimilation and cysteine biosynthesis in Pantoea sp. MT58

Reactions and Genes	dichromate 5 uM, aerobic
Phosphoglycerate dehydrogenase: 3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
IAI47_03725	-4.0
IAI47_07630	+0.0
IAI47_11750	-0.1
IAI47_19705	-0.0
IAI47_20620	-0.1
IAI47_20775	-0.2
Sulfate adenylyltransferase: sulfate + ATP + H+→adenosine 5'-phosphosulfate + diphosphate (EC 2.7.7.4)
IAI47_04180	-4.7
IAI47_04185	-4.2
Adenylyl-sulfate kinase: adenosine 5'-phosphosulfate + ATP→3'-phosphoadenylyl-sulfate + ADP + H+ (EC 2.7.1.25)
IAI47_04190	-4.7
Phosphoserine transaminase (in reverse): 3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
IAI47_12865	-4.1
Phosphoadenylyl-sulfate reductase (thioredoxin) (in reverse): 3'-phosphoadenylyl-sulfate + a reduced thioredoxin→sulfite + adenosine 3',5'-bisphosphate + an oxidized thioredoxin + 2 H+ (EC 1.8.4.8)
IAI47_04160	-3.6
Phosphoserine phosphatase: O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
IAI47_13095	+0.1
IAI47_16350	-4.2
Serine O-acetyltransferase: L-serine + acetyl-CoA→O-acetyl-L-serine + coenzyme A (EC 2.3.1.30)
IAI47_00745	N.D.
Sulfite reductase (NADPH) (in reverse): sulfite + 3 NADPH + 5 H+→hydrogen sulfide + 3 NADP+ + 3 H2O (EC 1.8.1.2)
IAI47_04150	-4.6
IAI47_04155	-4.8
IAI47_17225	-5.2
Cysteine synthase: O-acetyl-L-serine + hydrogen sulfide→L-cysteine + acetate + H+ (EC 2.5.1.47)
IAI47_05405	-4.3
IAI47_05440	-4.7
IAI47_14605	+0.3

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information