MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Methanococcus maripaludis JJ

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Reactions and Genes Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE
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2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A
(EC 6.2.1.5)
MMJJ_RS00185 N.D.
MMJJ_RS08640 N.D.
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
MMJJ_RS04735 N.D.
MMJJ_RS06400 -0.9
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
MMJJ_RS01675 -2.0
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate
(EC 2.6.1.1)
MMJJ_RS03215 N.D.
MMJJ_RS07170 -0.3
MMJJ_RS08090 N.D.
MMJJ_RS08820 -1.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information