MetaCyc Pathway: teichuronic acid biosynthesis (B. subtilis 168) in Sinorhizobium meliloti 1021

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Reactions and Genes Cobalt chloride 0.16 mM
remove
UDP-N-acetylglucosamine 4-epimerase:
UDP-N-acetyl-α-D-glucosamine→UDP-N-acetyl-α-D-galactosamine (EC 5.1.3.7)
SM_b20459 +0.0
SM_b20942 -0.2
SM_b21060 +0.0
SM_b21228 +0.0
SMa0715 +0.2
SMc00430 +0.0
SMc01324 +0.3
SMc02252 +0.2
SMc03963 +1.5
SMc04145 -0.2
UDP-glucose 6-dehydrogenase:
UDP-α-D-glucose + 2 NAD+ + H2O→UDP-α-D-glucuronate + 2 NADH + 3 H+ (EC 1.1.1.22)
SM_b21051 -0.0
SM_b21256 +0.9
SMc02641 -1.9
UDP-N-acetyl-α-D-galactosamine + di-trans,octa-cis-undecaprenyl phosphate→α-D-GalNAc-PP-Und + UMP (EC 2.7.8.40)
No genes
UDP-N-acetyl-α-D-galactosamine + α-D-GalNAc-PP-Und→α-D-GalNAc-(1→6)-α-D-GalNAc-diphospho-ditrans,octacis-undecaprenol + H+ + UDP
No genes
α-D-GalNAc-(1→6)-α-D-GalNAc-diphospho-ditrans,octacis-undecaprenol + UDP-α-D-glucuronate→β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und + H+ + UDP
No genes
β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und + UDP-α-D-glucuronate→β-D-GlcA-(1→4)-β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und + H+ + UDP
No genes
β-D-GlcA-(1→4)-β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und[in]→β-D-GlcA-(1→4)-β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und[out]
No genes
n β-D-GlcA-(1→4)-β-D-GlcA-(1→3)-α-D-GalNAc-(1→6)-α-D-GalNAc-PP-Und→a polyisoprenyl-wall teichuronic acid (B. subtilis 168) + n-1 H+ + n-1 di-trans,octa-cis-undecaprenyl diphosphate
No genes
a polyisoprenyl-wall teichuronic acid (B. subtilis 168) + Und-PP-[β-D-GlcNAc-(1→4)]-MurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala-D-Ala + H2O→a peptidoglycan-teichuronic acid complex (B. subtilis 168) + di-trans,octa-cis-undecaprenyl phosphate + 2 H+ + di-trans,octa-cis-undecaprenyl diphosphate (EC 2.7.8.M1)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information