MetaCyc Pathway: L-lysine degradation IV in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Paraquat dichloride 0.03 mg/ml
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Lysine 2-monooxygenase:
L-lysine + dioxygen→5-aminopentanamide + CO2 + H2O (EC 1.13.12.2)
Pf6N2E2_4778 -0.0
5-aminopentanamidase:
5-aminopentanamide + H2O→5-aminopentanoate + ammonium (EC 3.5.1.30)
Pf6N2E2_4777 -0.1
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
Pf6N2E2_373 -0.2
Pf6N2E2_4013 +1.7
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
Pf6N2E2_368 -0.0
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate (EC 2.8.3.13)
Pf6N2E2_4035 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information