MetaCyc Pathway: L-tyrosine degradation III in Sinorhizobium meliloti 1021

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Reactions and Genes NAG (C)
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine
(EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
SM_b20039 -0.2
SMa0387 -0.1
SMc00294 -4.7
SMc00387 -0.1
SMc00490 -1.5
SMc00710 -0.7
SMc01406 +0.2
SMc01578 -3.7
SMc01969 -0.1
SMc02251 -0.1
SMc02262 +0.0
SMc02393 +0.1
SMc03885 -0.2
SMc04323 +0.4
SMc04326 -0.1
SMc04386 -0.4
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2
(EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+
(EC 1.1.1.1)
SM_b20147 +0.1
SM_b20170 N.D.
SMa0263 -0.3
SMa1296 -0.0
SMa2113 +0.2
SMc00105 +0.1
SMc00680 +0.4
SMc01270 N.D.
SMc01582 +0.1
SMc01816 -0.2
SMc03929 -0.1
SMc04270 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information