MetaCyc Pathway: coenzyme M biosynthesis II in Sinorhizobium meliloti 1021

Reactions and Genes	NAG (C)
	remove
O-phospho-L-serine + H⁺ + sulfite→L-cysteate + phosphate (EC 2.5.1.76)
No genes
Aspartate transaminase: L-cysteate + 2-oxoglutarate→3-sulfopyruvate + L-glutamate (EC 2.6.1.1)
SM_b20039	-0.2
SMa0387	-0.1
SMa1495	-0.1
SMc00294	-4.7
SMc00490	-1.5
SMc01406	+0.2
SMc01578	-3.7
SMc01969	-0.1
SMc02251	-0.1
SMc02262	+0.0
SMc02393	+0.1
SMc04326	-0.1
SMc04386	-0.4
Sulfopyruvate decarboxylase: 3-sulfopyruvate + H⁺→sulfoacetaldehyde + CO₂ (EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H⁺ + H₂O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H⁺→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H₂O→coenzyme M + ammonium + pyruvate
No genes

Links:

Pathway details at MetaCyc
Fitness data for 13 genes
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All MetaCyc pathways for Sinorhizobium meliloti 1021

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information