MetaCyc Pathway: C4 photosynthetic carbon assimilation cycle, PEPCK type in Sinorhizobium meliloti 1021

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Reactions and Genes L-Lysine (C)
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Carbonate dehydratase (in reverse):
CO2 + H2O→hydrogen carbonate + H+
(EC 4.2.1.1)
SMa0045 +0.0
SMa1077 +0.1
SMc04083 N.D.
Phosphoenolpyruvate carboxylase (in reverse):
hydrogen carbonate + phosphoenolpyruvate→oxaloacetate + phosphate
(EC 4.1.1.31)
No genes
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
SM_b20039 -0.0
SMa0387 +0.0
SMa1495 -0.1
SMc00294 -1.4
SMc00490 +0.1
SMc01406 +0.1
SMc01578 -0.2
SMc01969 -0.0
SMc02251 +0.1
SMc02262 +0.1
SMc02393 -0.0
SMc04326 +0.0
SMc04386 -3.9
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (in reverse):
oxaloacetate + NADPH + H+→(S)-malate + NADP+
(EC 1.1.1.40; 1.1.1.82)
SMc00169 +0.2
SMc01126 -0.7
L-aspartate[in]→L-aspartate[out]
No genes
(S)-malate[in]→(S)-malate[out]
No genes
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)):
(S)-malate + NADP+→CO2 + pyruvate + NADPH
(EC 1.1.1.40)
SMc00169 +0.2
SMc01126 -0.7
Aspartate transaminase:
L-aspartate + 2-oxoglutarate→oxaloacetate + L-glutamate
(EC 2.6.1.1)
SM_b20039 -0.0
SMa0387 +0.0
SMc00294 -1.4
SMc00490 +0.1
SMc01406 +0.1
SMc01578 -0.2
SMc01969 -0.0
SMc02251 +0.1
SMc02262 +0.1
SMc02393 -0.0
SMc04326 +0.0
SMc04386 -3.9
Alanine transaminase (in reverse):
pyruvate + L-glutamate→L-alanine + 2-oxoglutarate
(EC 2.6.1.2)
SMc00294 -1.4
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→CO2 + phosphoenolpyruvate + ADP
(EC 4.1.1.49)
SMc02562 -7.3
L-alanine[in]→L-alanine[out]
No genes
phosphoenolpyruvate[in]→phosphoenolpyruvate[out]
No genes
Alanine transaminase (in reverse):
L-alanine + 2-oxoglutarate→pyruvate + L-glutamate
(EC 2.6.1.2)
No genes
Pyruvate, phosphate dikinase:
pyruvate + ATP + phosphate→phosphoenolpyruvate + AMP + diphosphate + H+
(EC 2.7.9.1)
SMc00025 -5.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information