MetaCyc Pathway: superpathway of L-phenylalanine biosynthesis in Sinorhizobium meliloti 1021

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Reactions and Genes L-Lysine (C)
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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
SMc00155 N.D.
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
SMc00696 N.D.
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
SMc01028 -7.7
SMc01343 N.D.
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
SM_b20037 +0.0
SMc02791 N.D.
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
SMc00695 N.D.
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
SMc00333 N.D.
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
SMc00007 N.D.
Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
SMc03858 N.D.
Prephenate dehydratase:
prephenate + H+→3-phenyl-2-oxopropanoate + CO2 + H2O (EC 4.2.1.51)
SMc02899 -8.3
Aspartate transaminase (in reverse):
3-phenyl-2-oxopropanoate + L-glutamate→L-phenylalanine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
SM_b20039 -0.0
SMa0387 +0.0
SMc00294 -1.4
SMc00387 -0.0
SMc00490 +0.1
SMc00710 -0.6
SMc01406 +0.1
SMc01578 -0.2
SMc01969 -0.0
SMc02251 +0.1
SMc02262 +0.1
SMc02393 -0.0
SMc03885 -0.1
SMc04323 -0.1
SMc04326 +0.0
SMc04386 -3.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information