MetaCyc Pathway: adipate biosynthesis in Burkholderia phytofirmans PsJN

Reactions and Genes	L-Tryptophan (C)
3-oxoadipyl-CoA thiolase: acetyl-CoA + succinyl-CoA→3-oxoadipoyl-CoA + coenzyme A (EC 2.3.1.174)
BPHYT_RS17345	-0.2
BPHYT_RS29385	-0.8
3-hydroxyacyl-CoA dehydrogenase (in reverse): 3-oxoadipoyl-CoA + NADH + H+→(3S)-hydroxyadipyl-CoA + NAD+ (EC 1.1.1.35)
BPHYT_RS03225	+0.2
BPHYT_RS06760	+0.3
BPHYT_RS09560	+0.0
BPHYT_RS13545	-0.4
BPHYT_RS28020	N.D.
BPHYT_RS34155	+0.5
Enoyl-CoA hydratase: (3S)-hydroxyadipyl-CoA→(2E)-5-carboxy-2-pentenoyl-CoA + H2O (EC 4.2.1.17)
BPHYT_RS02345	-0.2
BPHYT_RS03225	+0.2
BPHYT_RS03235	+0.2
BPHYT_RS03825	N.D.
BPHYT_RS06755	N.D.
BPHYT_RS06760	+0.3
BPHYT_RS08375	N.D.
BPHYT_RS08630	+0.2
BPHYT_RS09560	+0.0
BPHYT_RS10815	N.D.
BPHYT_RS11780	N.D.
BPHYT_RS13345	-0.1
BPHYT_RS13545	-0.4
BPHYT_RS14830	+0.1
BPHYT_RS17335	-0.0
BPHYT_RS17350	N.D.
BPHYT_RS20025	-0.3
BPHYT_RS25360	N.D.
BPHYT_RS25695	N.D.
BPHYT_RS27105	+0.2
BPHYT_RS27895	-0.3
BPHYT_RS28015	-0.3
BPHYT_RS28020	N.D.
BPHYT_RS28620	+0.5
BPHYT_RS35465	-2.4
(2E)-5-carboxy-2-pentenoyl-CoA + FADH2→adipoyl-CoA + FAD + H+
No genes
Succinate--CoA ligase (ADP-forming) (in reverse): adipoyl-CoA + ADP + phosphate→adipate + ATP + coenzyme A (EC 6.2.1.5)
BPHYT_RS16340	-3.4
BPHYT_RS16345	-2.9
BPHYT_RS21415	-0.4
BPHYT_RS21420	-0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information