MetaCyc Pathway: acetyl-CoA fermentation to butanoate in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Tryptophan (C)
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230 +0.1
BPHYT_RS03230 +0.3
BPHYT_RS08275 +0.0
BPHYT_RS09150 -1.3
BPHYT_RS09180 -0.0
BPHYT_RS09565 +0.6
BPHYT_RS17345 -0.2
BPHYT_RS21955 -0.6
BPHYT_RS29385 -0.8
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
BPHYT_RS21700 -0.1
BPHYT_RS27695 -0.1
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
BPHYT_RS06125 +0.0
BPHYT_RS26200 +0.5
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
BPHYT_RS00860 +0.1
BPHYT_RS09155 -0.3
BPHYT_RS15135 +0.7
BPHYT_RS27640 -0.2
BPHYT_RS29090 -0.1
3-hydroxybutyryl-CoA dehydratase:
(3R)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.55)
BPHYT_RS22375 +0.2
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
acetate + butanoyl-CoA→acetyl-CoA + butanoate (EC 2.8.3.1; 2.8.3.8)
BPHYT_RS07875 -0.1
BPHYT_RS20785 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information