MetaCyc Pathway: adipate degradation in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Succinate--CoA ligase (ADP-forming):
adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate
(EC 6.2.1.5)
BPHYT_RS16340 -4.4
BPHYT_RS16345 -3.8
BPHYT_RS21415 -0.4
BPHYT_RS21420 -0.1
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
BPHYT_RS03220 +0.0
BPHYT_RS07100 -0.1
BPHYT_RS18740 +0.1
BPHYT_RS20325 -0.1
BPHYT_RS35460 +0.1
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA
(EC 4.2.1.17)
BPHYT_RS02345 -0.1
BPHYT_RS03225 -0.0
BPHYT_RS03235 +0.3
BPHYT_RS03825 N.D.
BPHYT_RS06755 N.D.
BPHYT_RS06760 -1.3
BPHYT_RS08375 N.D.
BPHYT_RS08630 -0.0
BPHYT_RS09560 -0.2
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13345 -0.2
BPHYT_RS13545 -2.1
BPHYT_RS14830 +0.1
BPHYT_RS17335 -6.3
BPHYT_RS17350 N.D.
BPHYT_RS20025 -0.9
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 +0.1
BPHYT_RS27895 -0.4
BPHYT_RS28015 -0.2
BPHYT_RS28020 N.D.
BPHYT_RS28620 -0.5
BPHYT_RS35465 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+
(EC 1.1.1.35)
BPHYT_RS03225 -0.0
BPHYT_RS06760 -1.3
BPHYT_RS09560 -0.2
BPHYT_RS13545 -2.1
BPHYT_RS28020 N.D.
BPHYT_RS34155 +0.5
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA
(EC 2.3.1.174)
BPHYT_RS17345 -1.9
BPHYT_RS29385 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information