MetaCyc Pathway: 4-oxopentanoate degradation in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Butyrate--CoA ligase:
4-oxopentanoate + ATP + coenzyme A→4-oxopentanoyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
Butyrate--CoA ligase:
4-hydroxypentanoate + ATP + coenzyme A→4-hydroxypentanoyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
4-oxopentanoyl-CoA + NAD(P)H + H+→4-hydroxypentanoyl-CoA + NAD(P)+ (EC 1.1.1.M44)
No genes
4-hydroxypentanoyl-CoA + ATP→4-(phosphooxy)pentanoyl-CoA + ADP + H+ (EC 2.7.1.M16)
No genes
4-(phosphooxy)pentanoyl-CoA→3-pentenoyl-CoA + phosphate (EC 5.4.4.M2)
No genes
3-pentenoyl-CoA→(2E)-pent-2-enoyl-CoA (EC 5.4.4.M2)
No genes
(2E)-pent-2-enoyl-CoA + H2O→(3R)-3-hydroxypentanoyl-CoA (EC 5.4.4.M2)
No genes
Acetoacetyl-CoA reductase:
(3R)-3-hydroxypentanoyl-CoA + NADP+→3-oxopentanoyl-CoA + NADPH + H+ (EC 1.1.1.36)
BPHYT_RS00860 -0.1
BPHYT_RS09155 -1.0
BPHYT_RS27640 -0.0
BPHYT_RS29090 -0.2
Acetyl-CoA C-acyltransferase (in reverse):
3-oxopentanoyl-CoA + coenzyme A→propanoyl-CoA + acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230 +0.1
BPHYT_RS03230 -0.1
BPHYT_RS08275 -0.1
BPHYT_RS09150 -0.1
BPHYT_RS09180 -0.2
BPHYT_RS09565 +0.8
BPHYT_RS17345 -1.9
BPHYT_RS21955 +0.3
BPHYT_RS29385 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information