MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
BPHYT_RS09910 +0.4
BPHYT_RS31410 -0.1
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
BPHYT_RS31410 -0.1
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
BPHYT_RS00120 -0.1
BPHYT_RS00395 -0.1
BPHYT_RS05370 +0.4
BPHYT_RS07490 -0.4
BPHYT_RS09900 +0.2
BPHYT_RS17340 -6.3
BPHYT_RS18745 +0.1
BPHYT_RS19710 -0.1
BPHYT_RS20795 +0.3
BPHYT_RS25705 +0.1
BPHYT_RS25810 -0.4
BPHYT_RS27405 -0.3
BPHYT_RS28770 +0.2
BPHYT_RS29875 +0.0
BPHYT_RS30510 +0.1
BPHYT_RS32650 +0.2
BPHYT_RS34980 -0.1
BPHYT_RS35600 +0.0
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
BPHYT_RS10745 N.D.
BPHYT_RS30300 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information