MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Burkholderia phytofirmans PsJN

Reactions and Genes	L-Phenylalanine (C)
Acetyl-CoA C-acyltransferase: 2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230	+0.1
BPHYT_RS03230	-0.1
BPHYT_RS08275	-0.1
BPHYT_RS09150	-0.1
BPHYT_RS09180	-0.2
BPHYT_RS09565	+0.8
BPHYT_RS17345	-1.9
BPHYT_RS21955	+0.3
BPHYT_RS29385	-0.2
3-hydroxyacyl-CoA dehydrogenase (in reverse): acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
BPHYT_RS03225	-0.0
BPHYT_RS06760	-1.3
BPHYT_RS09560	-0.2
BPHYT_RS13545	-2.1
BPHYT_RS28020	N.D.
BPHYT_RS34155	+0.5
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
BPHYT_RS02345	-0.1
BPHYT_RS03225	-0.0
BPHYT_RS03235	+0.3
BPHYT_RS03825	N.D.
BPHYT_RS08375	N.D.
BPHYT_RS08630	-0.0
BPHYT_RS09560	-0.2
BPHYT_RS10815	N.D.
BPHYT_RS11780	N.D.
BPHYT_RS13545	-2.1
BPHYT_RS14830	+0.1
BPHYT_RS25360	N.D.
BPHYT_RS25695	N.D.
BPHYT_RS27105	+0.1
BPHYT_RS27895	-0.4
BPHYT_RS28620	-0.5
BPHYT_RS35465	-0.1
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse): crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+ (EC 1.3.1.44)
BPHYT_RS00670	+0.2
BPHYT_RS02220	+0.1
BPHYT_RS03000	+0.0
BPHYT_RS08290	+0.2
BPHYT_RS08510	+0.1
BPHYT_RS20325	-0.1
BPHYT_RS20780	-0.0
BPHYT_RS25370	-0.4
BPHYT_RS25400	-0.1
BPHYT_RS28040	+0.1
Butanal dehydrogenase (in reverse): butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information