MetaCyc Pathway: L-phenylalanine degradation IV (mammalian, via side chain) in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Aromatic-L-amino-acid decarboxylase:
L-phenylalanine + H+→2-phenylethylamine + CO2 (EC 4.1.1.28; 4.1.1.53)
BPHYT_RS34205 -0.0
Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
BPHYT_RS00155 +0.1
BPHYT_RS02830 -0.0
BPHYT_RS04100 N.D.
BPHYT_RS05430 -0.0
BPHYT_RS05975 -0.2
BPHYT_RS06770 -0.2
BPHYT_RS06900 -5.8
BPHYT_RS08040 +0.0
BPHYT_RS08950 -1.7
BPHYT_RS09580 -0.2
BPHYT_RS10265 -0.0
BPHYT_RS10440 -0.2
BPHYT_RS13065 +0.1
BPHYT_RS13450 -0.4
BPHYT_RS14905 -1.2
BPHYT_RS15405 +0.0
BPHYT_RS15820 +0.2
BPHYT_RS17705 -0.2
BPHYT_RS21060 -0.2
BPHYT_RS21560 +0.1
BPHYT_RS21610 -0.0
BPHYT_RS21730 +0.2
BPHYT_RS22065 -0.1
BPHYT_RS22425 -0.1
BPHYT_RS26535 -0.1
BPHYT_RS26755 -0.0
BPHYT_RS27000 -0.0
BPHYT_RS28370 +0.0
BPHYT_RS28685 +0.3
BPHYT_RS28695 +0.1
BPHYT_RS30590 -0.3
BPHYT_RS30680 +0.1
BPHYT_RS32285 -0.2
BPHYT_RS32640 -0.0
BPHYT_RS35285 -0.2
4-hydroxyphenylpyruvate dioxygenase:
3-phenyl-2-oxopropanoate + dioxygen→(2-hydroxyphenyl)acetate + CO2 (EC 1.13.11.27)
BPHYT_RS18295 +0.2
BPHYT_RS22675 +0.2
BPHYT_RS33445 -0.1
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Primary-amine oxidase:
2-phenylethylamine + dioxygen + H2O→phenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.21; 1.4.3.4)
BPHYT_RS09910 +0.4
Phenylacetaldehyde dehydrogenase:
phenylacetaldehyde + NAD+ + H2O→phenylacetate + NADH + 2 H+ (EC 1.2.1.39)
BPHYT_RS09900 +0.2
Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate (EC 6.2.1.30)
BPHYT_RS17360 -0.1
Glutamine N-phenylacetyltransferase:
phenylacetyl-CoA + L-glutamine→α-N-phenylacetyl-L-glutamine + coenzyme A + H+ (EC 2.3.1.14)
No genes
phenylacetyl-CoA + glycine→phenylacetylglycine + coenzyme A + H+ (EC 2.3.1.192)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information