MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
BPHYT_RS34205 -0.0
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
BPHYT_RS00120 -0.1
BPHYT_RS00395 -0.1
BPHYT_RS05370 +0.4
BPHYT_RS07490 -0.4
BPHYT_RS09900 +0.2
BPHYT_RS17340 -6.3
BPHYT_RS18745 +0.1
BPHYT_RS19710 -0.1
BPHYT_RS20795 +0.3
BPHYT_RS25705 +0.1
BPHYT_RS25810 -0.4
BPHYT_RS27405 -0.3
BPHYT_RS28770 +0.2
BPHYT_RS29875 +0.0
BPHYT_RS30510 +0.1
BPHYT_RS32650 +0.2
BPHYT_RS34980 -0.1
BPHYT_RS35600 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information