MetaCyc Pathway: 4-methylcatechol degradation (ortho cleavage) in Burkholderia phytofirmans PsJN

Add experiment(s):


Reactions and Genes L-Phenylalanine (C)
remove
4-methylcatechol + dioxygen→3-methyl-cis,cis-muconate + 2 H+
No genes
Chloromuconate cycloisomerase (in reverse):
3-methyl-cis,cis-muconate + H+→4-methylmuconolactone (EC 5.5.1.7)
No genes
4-carboxymethyl-4-methylbutenolide mutase:
4-methylmuconolactone→3-methylmuconolactone (EC 5.4.99.14)
No genes
Muconolactone Delta-isomerase:
3-methylmuconolactone→4-methyl-3-oxoadipate-enol-lactone (EC 5.3.3.4)
BPHYT_RS07835 +0.6
BPHYT_RS10665 N.D.
3-oxoadipate enol-lactonase:
4-methyl-3-oxoadipate-enol-lactone + H2O→4-methyl-3-oxoadipate + H+ (EC 3.1.1.24)
BPHYT_RS02320 +0.0
BPHYT_RS21430 N.D.
BPHYT_RS34955 N.D.
3-oxoadipate CoA-transferase:
4-methyl-3-oxoadipate + succinyl-CoA→4-methyl-3-oxoadipyl-CoA + succinate (EC 2.8.3.6)
BPHYT_RS21415 -0.4
BPHYT_RS21420 -0.1
3-oxoadipyl-CoA thiolase (in reverse):
4-methyl-3-oxoadipyl-CoA + coenzyme A→acetyl-CoA + (2S)-methylsuccinyl-CoA (EC 2.3.1.174)
BPHYT_RS17345 -1.9
BPHYT_RS29385 -0.2

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information