MetaCyc Pathway: catechol degradation III (ortho-cleavage pathway) in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Catechol 1,2-dioxygenase:
catechol + dioxygen→cis,cis-muconate + 2 H+ (EC 1.13.11.1)
BPHYT_RS07850 +0.3
BPHYT_RS10670 +0.3
BPHYT_RS20450 +0.0
Muconate cycloisomerase (in reverse):
cis,cis-muconate + H+→(+)-muconolactone (EC 5.5.1.1)
BPHYT_RS07840 +0.2
BPHYT_RS10675 -0.1
Muconolactone Delta-isomerase:
(+)-muconolactone→(4,5-dihydro-5-oxofuran-2-yl)-acetate (EC 5.3.3.4)
BPHYT_RS07835 +0.6
BPHYT_RS10665 N.D.
3-oxoadipate enol-lactonase:
(4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O→3-oxoadipate + H+ (EC 3.1.1.24)
BPHYT_RS02320 +0.0
BPHYT_RS21430 N.D.
BPHYT_RS34955 N.D.
3-oxoadipate CoA-transferase:
3-oxoadipate + succinyl-CoA→3-oxoadipoyl-CoA + succinate (EC 2.8.3.6)
BPHYT_RS21415 -0.4
BPHYT_RS21420 -0.1
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→acetyl-CoA + succinyl-CoA (EC 2.3.1.174)
BPHYT_RS17345 -1.9
BPHYT_RS29385 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information