MetaCyc Pathway: glutaryl-CoA degradation in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+→(E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.6)
No genes
(E)-glutaconyl-CoA + H+→crotonyl-CoA + CO2 (EC 1.3.8.6)
No genes
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150)
BPHYT_RS02345 -0.1
BPHYT_RS03225 -0.0
BPHYT_RS03235 +0.3
BPHYT_RS03825 N.D.
BPHYT_RS08375 N.D.
BPHYT_RS08630 -0.0
BPHYT_RS09560 -0.2
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13545 -2.1
BPHYT_RS14830 +0.1
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 +0.1
BPHYT_RS27895 -0.4
BPHYT_RS28620 -0.5
BPHYT_RS35465 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
BPHYT_RS03225 -0.0
BPHYT_RS06760 -1.3
BPHYT_RS09560 -0.2
BPHYT_RS13545 -2.1
BPHYT_RS28020 N.D.
BPHYT_RS34155 +0.5
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
BPHYT_RS02230 +0.1
BPHYT_RS03230 -0.1
BPHYT_RS08275 -0.1
BPHYT_RS09150 -0.1
BPHYT_RS09180 -0.2
BPHYT_RS09565 +0.8
BPHYT_RS17345 -1.9
BPHYT_RS21955 +0.3
BPHYT_RS29385 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information