MetaCyc Pathway: propanoate fermentation to 2-methylbutanoate in Burkholderia phytofirmans PsJN

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Reactions and Genes L-Phenylalanine (C)
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Propionate CoA-transferase:
propanoate + acetyl-CoA→acetate + propanoyl-CoA (EC 2.8.3.1)
BPHYT_RS20785 -0.0
Acetyl-CoA C-acyltransferase:
propanoyl-CoA + acetyl-CoA→2-methylacetoacetyl-CoA + coenzyme A (EC 2.3.1.16)
BPHYT_RS02230 +0.1
BPHYT_RS03230 -0.1
BPHYT_RS08275 -0.1
BPHYT_RS09150 -0.1
BPHYT_RS09180 -0.2
BPHYT_RS09565 +0.8
BPHYT_RS17345 -1.9
BPHYT_RS21955 +0.3
BPHYT_RS29385 -0.2
3-hydroxy-2-methylbutyryl-CoA dehydrogenase (in reverse):
2-methylacetoacetyl-CoA + NADH + H+→(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD+ (EC 1.1.1.178)
BPHYT_RS03225 -0.0
BPHYT_RS06760 -1.3
BPHYT_RS09560 -0.2
BPHYT_RS13545 -2.1
BPHYT_RS15890 -0.2
BPHYT_RS28020 N.D.
BPHYT_RS34155 +0.5
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA→(E)-2-methylcrotonoyl-CoA + H2O (EC 4.2.1.150)
BPHYT_RS02345 -0.1
BPHYT_RS03225 -0.0
BPHYT_RS03235 +0.3
BPHYT_RS03825 N.D.
BPHYT_RS08375 N.D.
BPHYT_RS08630 -0.0
BPHYT_RS09560 -0.2
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13545 -2.1
BPHYT_RS14830 +0.1
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 +0.1
BPHYT_RS27895 -0.4
BPHYT_RS28020 N.D.
BPHYT_RS28620 -0.5
BPHYT_RS35465 -0.1
(E)-2-methylcrotonoyl-CoA + a reduced electron-transfer flavoprotein→(2S)-2-methylbutanoyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.5)
No genes
(2S)-2-methylbutanoyl-CoA + H2O→2-methylbutanoate + coenzyme A + H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information