MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Paraburkholderia graminis OAS925

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Reactions and Genes 2-Deoxy-D-Ribose (C)
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L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
No genes
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
ABIE53_002576 -0.4
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
ABIE53_000363 -0.1
ABIE53_001340 +0.4
ABIE53_002266 -1.8
ABIE53_002377 +0.4
ABIE53_003630 -0.2
ABIE53_004612 -0.0
ABIE53_005029 -0.0
ABIE53_005080 -0.5
ABIE53_005142 +0.2
ABIE53_005143 -0.3
ABIE53_005608 -0.2
ABIE53_005631 +0.2
ABIE53_005633 -0.3
ABIE53_005650 -0.1
ABIE53_006339 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information